DETROIT — Everything changed in less than two minutes Wednesday night at Joe Louis Arena.

Right wingers Tomas Jurco and Gustav Nyquist scored in a 1:42 span in the third period, and goaltender Jimmy Howard made 33 saves to give the Detroit Red Wings a 3-2, come-from-behind win over the Boston Bruins.

Nyquist and Howard are former University of Maine hockey stars.

“That was fun,” Nyquist said. “That was a really good comeback there. It was great to see. The crowd was really into it, too, so that was awesome to see.”

The loss snapped Boston’s franchise-record, nine-game road winning streak. Boston suffered its first regulation loss in 17 games (15-1-1).

“It sucks,” said Boston goalie Tuukka Rask, who made 17 saves. “We don’t want to lose games, even if we win 20 in a row.”

Winger Tomas Tatar added a goal and an assist for Detroit (36-26-14), which is in the seventh playoff spot in the Eastern Conference.

“They were all over us in the first period,” Jurco said. “They played great, but this is what the good teams do, we came back and scored some huge goals. It’s obviously great for us and obviously great for our mentality, and of course, great for the standings.”

Defenseman Johnny Boychuk and center Carl Soderberg scored for Boston (52-18-6).

“I thought we let our guard down the second part of the third and they capitalized on it,” Bruins coach Claude Julien said. “Their goalie kept them in it as long as he had to, and when we got sloppy, they took advantage of it.”

Jurco tied the game 2-2 with 8:54 left in the third. He put in a shot from a goal-mouth scramble after Tatar kicked the puck across the crease to him. It was Jurco’s sixth goal.

“It was a scrum in front of the net,” Jurco said. “They defenseman had it somewhere in the jersey or somewhere … and then we tried to push in to get the puck. Finally, it landed and I shoot it. … But I kind of fanned on it, and Tats (Tatar) kicked it in front of the net right on my stick. So it was a good play I think.”

The red-hot Nyquist then scored the winner on a spectacular, unassisted, end-to-end rush with 7:12 left. He picked up a loose puck inside the Detroit blue line, raced past Boston defenseman Zdeno Chara and beat Rask from the bottom of the left circle to give the Red Wings the lead.

“I think (Chara) came off the bench, so it was tough for him to get enough time to gap up, got kind of flat-footed,” Nyquist said. “I just tried to use my speed. I came with pretty good speed, so I skated around him wide and I was in alone and just tried to get a quick shot off underneath the glove, and I saw it go in.”

It was Nyquist’s 28th goal of the season, his 12th in his past 10 games and 23rd in his past 28 games.

Soderberg’s power-play goal gave the Bruins a 2-1 lead 1:10 into the third period. He beat Howard with a wrist shot from the bottom of the left circle. It was Soderberg’s 16th goal.

Tatar tied the game, 1-1, at 4:45 of the second period with a screened wrist shot from the high slot. It was his 19th goal and came just as Bruins center Patrice Bergeron’s hooking penalty ended, so it was an even-strength goal.

Detroit defenseman Jakub Kindl hit the goal post 2:44 into the second period.

Boychuk opened the scoring with 3:10 remaining in the opening period on a screened slap shot from the point. It was his fourth goal.

NOTES: Boston RW Jarome Iginla was named the NHL’s First Star for March. He led the league with 13 goals during the month and added four assists in 17 games. Iginla didn’t play Wednesday due to a minor lower-body injury. Coach Claude Julien said Iginla was day-to-day. … Nyquist was the league’s Second Star for March. He had 12 goals and six assists in 15 games. … Bruins D Torey Krug played at Michigan State and is from the Detroit suburb of Livonia. … Red Wings RW Daniel Alfredsson did not play because of an undisclosed lower-body injury. He is day-to-day. … Boston RW Reilly Smith and Detroit D Brendan Smith are brothers. … Detroit LW Drew Miller played his 400th game.