SEARSPORT, Maine — Two people were taken to the hospital Monday afternoon after a nearly head-on collision on U.S. Route 1, which was closed by police in the crash’s aftermath because traffic on the busy coastal roadway had backed up for miles.

The collision occurred at 2:38 p.m. near the Hobby Horse Flea Market at 383 East Main St., according to Searsport Police Chief Dick LaHaye. A man driving a Jeep Wrangler allegedly went around a car that had stopped to turn into the flea market and crossed over the center line, colliding nearly head-on with a woman driving a Honda CRV. Both vehicles were reportedly traveling at about 45 mph.

“It’s unclear at this point, but there [also] may have been a medical issue,” LaHaye said Monday afternoon of the Jeep driver.

Donald McKillop Jr., 66, of Penobscot, who was driving the Jeep, suffered multiple injuries in the accident, the chief said. He was taken to Waldo County General Hospital in Belfast and from there, LaHaye believed he was taken by LifeFlight to Eastern Maine Medical Center in Bangor.

The driver of the other vehicle, Jamie Fraser, 36, of Searsport, was taken to Waldo County General Hospital by Searsport Ambulance. She had lacerations on her leg and across her body, according to the chief. She was traveling with two children, ages 6 and 7, in her vehicle. They were checked at the site of the crash by Searsport Ambulance and released to relatives, LaHaye said.

Both vehicles were totaled, and while emergency responders were working at the crash site, traffic on Route 1 was limited to one lane only. That created long lines of cars backed up all the way into Searsport, LaHaye said, and at about 5:30 p.m., police decided to close the road and reroute traffic altogether.

The Maine State Police are reconstructing the accident, the chief said, and crews from Searsport Fire, Searsport Ambulance, Belfast Ambulance, Stockton Springs Ambulance and the Stockton Springs Police Department also assisted at the scene.