BRUNSWICK, Maine — Two years after a Beverly Hills real estate agent listed it for $3 million, a 1780 home that the owners claim Harriet Beecher Stowe lived in while writing “Uncle Tom’s Cabin” is on the market again, this time for $1.6 million.

Bowdoin College, which owns all the surrounding properties, is reportedly interested.

As first reported by the college’s student newspaper, The Bowdoin Orient, the five-bedroom Colonial at 28 College St. — the only property on that street not yet owned by Bowdoin College — was listed Wednesday by David J. Jones of F.O. Bailey Real Estate for $1.6 million.

According to the listing, the 3,500-square-foot home is “a significant piece of American History.” In addition to allegedly serving as Stowe’s home while she wrote the abolitionist novel, the listing claims Franklin and Eleanor Roosevelt, Robert Frost, Carl Sandburg, Chris Wallace and William Cohen have stayed in the house.

In 2014, homeowner Arline Pennell Lay told The Times Record that Stowe rented a second-floor room in the house, then on Park Row, to write away from her large family..

Katy Longley, Bowdoin’s senior vice president for finance and administration and treasurer, told The Orient, “The house is for sale, the college has an option to acquire it, and we intend to acquire it.”

Two years ago, the house was listed for $3 million by a California real estate agent who claimed that Stowe had written “the bulk” of the book while living there.

Bowdoin officials said at the time that Stowe wrote the book at the Federal Street home where she lived from 1851 to 1852, and they said the asking price was inflated.

The property is assessed at $154,300, which is 70 percent of the estimated market value, according to Angie Bradstreet in the town’s assessing office.