PRESQUE ISLE, Maine — Two people were charged with drug crimes Wednesday after the Maine Drug Enforcement Agency seized a significant amount of heroin in Aroostook County for the second time in two weeks.

Agents arrested Katie Ramus, 37, of Presque Isle and Norberto Colon, 31, of Brockton, Massachusetts, and seized $5,000 worth of heroin, Department of Public Safety Spokesman Stephen McCausland said in a statement issued Thursday.

Ramus was on probation for an unrelated charge, which allowed agents involved a heroin investigation to search her home. Colon, who was on bail for an unspecified charge, was inside the home at the time.

Peter Arno, MDEA commander, said that agents located nearly 13 grams of heroin with a street value of $5,000, both inside the house and in Colon’s car, which was parked in the driveway. Agents suspect Colon brought the heroin to Presque Isle in what appears to be a growing trend of out-of-state drug dealers using Maine homes as a base of operation, according to the MDEA.

Just last month, a Florida resident who was released from a Miami prison in February, wanted on several outstanding warrants from that state, was arrested in Fort Fairfield and charged with trafficking in heroin.

In that case, Ignacio D. Roque, 37, was charged after agents found more than two ounces of bulk unpackaged heroin with a street value of more than $20,000 inside his apartment, according to Arno.

Colon has been charged with aggravated trafficking in heroin, and violations of conditions of release. Ramus was charged with possession of heroin and a probation violation.

Both Colon and Ramus were taken to the Aroostook County Jail in Houlton.

Maine probation officers assisted MDEA agents during this ongoing heroin investigation conducted by the MDEA Aroostook County Task Force office in Houlton. More arrests are possible, according to police.