Two more Mainers have died and another 1,524 coronavirus cases reported across the state, Maine health officials said Wednesday.

Wednesday’s report brings the total number of coronavirus cases in Maine to 169,998, according to the Maine Center for Disease Control and Prevention. That’s up from 168,474 on Tuesday.

Of those, 124,858 have been confirmed positive, while 45,140 were classified as “probable cases,” the Maine CDC reported.

A man and woman in their 70s and 80s from Cumberland and York counties have succumbed to the virus, bringing the statewide death toll to 1,716.

The number of coronavirus cases diagnosed in the past 14 days statewide is 13,466. This is an estimation of the current number of active cases in the state, as the Maine CDC is no longer tracking recoveries for all patients. That’s up from 13,319 on Tuesday.

The new case rate statewide Wednesday was 11.39 cases per 10,000 residents, and the total case rate statewide was 1,270.15.

Maine’s seven-day average for new coronavirus cases is 1,029.6, down from 1,031 the day before, up from 908.6 a week ago and up from 766.7 a month ago.

The most cases have been detected in Mainers younger than 20, while Mainers over 80 years old account for the largest portion of deaths. More cases have been recorded in women and more deaths in men.

So far, 3,833 Mainers have been hospitalized at some point with COVID-19, the illness caused by the new coronavirus. Of those, 408 are currently hospitalized, with 88 in critical care and 38 on a ventilator. Overall, 58 out of 377 critical care beds and 220 out of 321 ventilators are available.

The total statewide hospitalization rate on Wednesday was 28.64 patients per 10,000 residents.

Cases have been reported in Androscoggin (17,228), Aroostook (8,222), Cumberland (34,392), Franklin (4,311), Hancock (4,998), Kennebec (16,403), Knox (4,037), Lincoln (3,579), Oxford (8,528), Penobscot (19,343), Piscataquis (2,186), Sagadahoc (3,506), Somerset (7,226), Waldo (4,232), Washington (3,048) and York (28,758) counties. Information about where an additional case was reported wasn’t immediately available.

An additional 1,888 vaccine doses were administered in the previous 24 hours. As of Wednesday, 973,376 Mainers are fully vaccinated, or about 76 percent of eligible Mainers, according to the Maine CDC.

As of Wednesday morning, the coronavirus had sickened 72,195,617 people in all 50 states, the District of Columbia, Puerto Rico, Guam, the Northern Mariana Islands and the U.S. Virgin Islands, as well as caused 872,370 deaths, according to the Johns Hopkins University of Medicine.